Case Studies

Learn how Nikalyte’s advanced PVD systems and nanoparticle deposition technologies are impacting industries like biotechnology and environmental monitoring. Our case studies offer insights into the challenges we’ve helped clients overcome. We also showcase the innovative solutions we’ve developed using our technology.

Nanoparticle Coatings for Infection-Resistant Titanium Implants

Case Studies / By

Industry: Biomedical / Orthopaedic and Dental Implants Challenge: Titanium alloys such as Ti6Al4V are the material of choice for orthopaedic and dental implants, valued for their mechanical strength, corrosion resistance, and biocompatibility. However, their bioinert nature means they cannot chemically bond with surrounding bone tissue, and implant-associated bacterial infections remain a leading cause of revision […]

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Nikalyte’s Alloy Nanoparticle UHV Deposition Source at the University of Oxford

High-Entropy Alloy Catalysts for Green Hydrogen Production

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Image Description: Nikalyte’s Alloy Nanoparticle UHV (Ultra-High Vacuum) Deposition Source at the University of Oxford, with Peixi Cong and Leanne Jones (Postdoctoral Fellows). Industry: Green Energy / Hydrogen Production / Nanomaterials Challenge: As global efforts ramp up towards decarbonization, efficient hydrogen production from water electrolysis becomes increasingly important. A major barrier to scaling up water

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Nikalyte_AEMWE (Alkaline Anion Exchange Membrane Water Electrolyzer) cell

Low Cost Electrocatalysts for Hydrogen Production from Water

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Image Description: Copper nanoparticle coating on surgical wound dressings using Nikalyte, reducing MRSA colony formation. Industry: Healthcare / Wound Healing / Antibacterial Solutions Challenge: The client, an NHS Research Hospital, faced significant challenges in preventing and treating Methicillin-Resistant Staphylococcus aureus (MRSA) infections in wound care. They were looking for a solution to enhance the effectiveness

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Copper Nanoparticles using Nikalyte for Wound Healing NHS

Copper Nanoparticles for Wound Healing – NHS Case Study

Case Studies / By

Image Description: Copper nanoparticle coating on surgical wound dressings using Nikalyte, reducing MRSA colony formation. Industry: Healthcare / Wound Healing / Antibacterial Solutions Challenge: The client, an NHS Research Hospital, faced significant challenges in preventing and treating Methicillin-Resistant Staphylococcus aureus (MRSA) infections in wound care. They were looking for a solution to enhance the effectiveness

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Gold Electrodes for Glucose Sensors

Case Studies / By

Industry: Biomedical / Sensors Challenge: Our client faced challenges with the performance of enzymatic glucose biosensors, particularly in terms of current transport efficiency and sensor sensitivity. Traditional electrode designs were limiting the accuracy and precision of the biosensor. Image Description: Thin-film gold (Au) electrode surface coated with gold nanoparticles using Nikalyte NL50, enhancing surface area

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Nano-Silver Bonding for High-Power Electronics Packaging

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Industry: Electronics / Semiconductor Packaging / Advanced Materials Challenge: Loughborough University, led by Prof. Changqing Liu, sought to address the growing demand for advanced interconnect materials in electronics packaging. Specifically, there was a need for low-temperature, fast bonding solutions that could withstand high temperatures and high-power density environments, such as those used in wide bandgap

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Ultra-Sensitive NO2 MOF Sensors for Security & Diagnostics

Ultra-Sensitive NO2 MOF Sensors for Security & Diagnostics

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Image Description: Ultra-sensitive NO2 MOF sensors designed for security and diagnostic applications. Industry: Environmental Monitoring / Security / Sensor Technology Challenge: In work recently published, by Lister et al. from the Materials department at Oxford University researchers  developed ultra-sensitive gas sensors capable of detecting trace concentrations of NO2 gas for applications in security, pollution monitoring,

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SARS‐CoV‐2 Screening Using Nikalyte's SERS Flexible Sensors

Flexible SERS Sensors for SARS-CoV-2 Detection on Facemasks

Case Studies / By

Image Description: SERS flexible sensor for SARS-CoV-2 screening, utilizing gold nanoparticles on facemasks for enhanced detection of the virus’ spike protein. Industry: Healthcare / Diagnostics / Nanotechnology Challenge: Nikalyte collaborated with Dr. Wangcun Jia at the University of California, Irvine,  on research project to develop a reliable and low-cost solution for SARS-CoV-2 screening using flexible

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Copper Nanoparticle Coated on Surgical Gloves using Niklayte

Copper Nanoparticle Coatings for E. coli in Surgical Gloves

Case Studies / By

Image Description: Copper nanoparticle coating on surgical gloves using Nikalyte, enhancing antimicrobial properties for superior E. coli eradication. Industry: Healthcare / Nanotechnology / Antimicrobial Solutions Challenge: The client sought to enhance the antimicrobial properties of surgical gloves to combat E. coli infections. They needed a solution that would improve the gloves’ ability to eradicate harmful

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Nanoporous Gold Electrodes for DNA Sequencing Technology

Case Studies / By

Industry: Biomedical / DNA Sequencing / Nanotechnology Challenge: The client sought to enhance the performance of Cr-Au electrodes used in DNA sequencing, particularly to increase the surface area of gold for improved RNA bonding. Their goal was to achieve a significant improvement in electrode performance, specifically a 50-fold increase in surface area, to enhance the

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