Industry: Biomedical / Sensors
Challenge:
Our client faced challenges with the performance of enzymatic glucose biosensors, particularly in terms of current transport efficiency and sensor sensitivity. Traditional electrode designs were limiting the accuracy and precision of the biosensor.

Image Description: Thin-film gold (Au) electrode surface coated with gold nanoparticles using Nikalyte NL50, enhancing surface area and conductivity for electrochemical and sensing applications.
Solution:
Nikalyte provided a solution by developing nanostructured gold electrodes using gold nanoparticles, designed to enhance enzyme attachment. By using covalent bonding between the enzymes and the electrodes, we significantly improved current transport and sensor sensitivity. Additionally, this technology could be extended to enable segregated attachment of a variety of biomolecules, making it possible to perform biosensor multiplexing on a single chip—an advancement for future sensor applications.

Image Description: Electrochemical testing setup demonstrating the configuration used to evaluate Nikalyte-fabricated gold (Au) electrodes
Results:
The custom-designed nanostructured electrodes led to a 10x increase in effective surface area compared to traditional planar gold thin film electrode, enhancing the sensor’s sensitivity and accuracy. These improvements positioned our solution as a next-generation technology for biosensors in the medical field.
Note: Full details of the reports are confidential and protected under an NDA.

Image Description: SEM image of a thin-film gold (Au) electrode coated with gold nanoparticles, showing enhanced surface roughness for improved electrochemical performance.
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